What is the CBD Entourage Effect?

Hemp is one of the most multifunctional plants on earth. Hemp contains a huge phytocomplex of cannabinoids, all of which are of particular importance to the consumer.

Although the most common cannabinoids have been extensively studied in isolation, researchers are now quickly discovering that the benefits of CBD are enhanced by subordinate cannabinoids and terpenes.

This synergistic effect is known as the "entourage effect" when cannabinoids combine they produce even greater results than they can individually. Ethan B. Russo coined the term as a result of a study in the British Journal of Pharmacology in 2001, when he discovered how psychoactive cannabinoids can be tamed.

The Entourage Effect is based on the concept of plant synergy. In the case of hemp, the individual effective compounds come together and promote each other to a level that they alone could not achieve.

This phenomenon is most evident in the study of the mutual relationship between psychoactive cannabinoids and CBD.

How does CBD affect the psychoactive effect?

CBD is particularly promising in mediating the adverse effects of psychoactive cannabinoid THC. In contrast to the feelings of anxiety and paranoia that psychoactive cannabinoids may cause or exacerbate, CBD exerts a mild sedative effect that helps to reduce the aforementioned adverse symptoms.

Recently, some manufacturers of CBD products have decided to use 99% CBD crystals to advertise high levels of cannabidiol in their products. Other manufacturers, by contrast, choose the more scientific approach by naturally extracting cannabinoids and terpenes from whole hemp plants using CO₂ extraction.

Terpene: surprisingly useful

Like cannabinoids, terpenes also have a major impact on the efficacy of CBD products. Over 200 of these terpenes are naturally found in cannabis varieties. These pungent, protective molecules are important for the structural development of the plant and for consumers.

Apart from the trichomes of their flowers, terpenes are not only found in hemp. In fact, they populate all of nature in the form of essential oils.

Hops, citrus fruits and evergreen trees - all contain different amounts of these molecules. It is believed that the earth's living beings produce over 20,000 terpenes, including many of the world's best-known fragrances.

The best-known terpenes are probably for their diverse sharp flavors, which include characteristic odors from the pine to the clove.

However, they also exert direct effects on the success of the crop cultivation cycle. Namely, terpenes act as a form of natural protection for hemp plants, keeping away pests and disease while attracting selected pollinators.

Because of these useful properties, terpenes are extracted and used by organic gardeners as biological pesticides.

The entourage effect of CBD oil

The CBD oils that are available on the market today really cover the entire scale in terms of their quality. Reputable CBD manufacturers are therefore struggling to make sure that their high-quality CBD oils with the full spectrum of effective compounds do not sink into a sea of ​​mediocre products from inexperienced producers.

There is a world of difference between taking CBD supplements with terpenes and other cannabinoids and taking products made with CBD isolates alone.

While cheap oils are likely to be tagged with a lower price tag, customers will only get supplements for their money that are less beneficial to a healthy diet.

The manufacturers of hemp supplements had a lot of lost time to catch up because they were stigmatized for decades due to the illegal nature of high-psychoactive cannabis strains.

Meanwhile, more and more people understand how to use CBD as a beneficial supplement to human nutrition and that it can be taken, above all, safely. Looking ahead, the Entourage Effect becomes incredibly important because it will shape the future of hemp as a therapeutically effective agent.


As we already know, CBD stands for a specific molecule  that is extracted from the hemp plant. Cannabidiol or CBD belongs to the group of cannabinoids, of which at least 113 different occur in the hemp plant.

Furthermore, there are numerous other substances in the plant, such as the terpenes.

A majority of researchers in this field believe that the interaction of cannabinoids and terpenes has a more effective effect than single, isolated cannabinoids (for example, CBD). This effect is called entourage effect.

Therefore, it is advisable to choose a manufacturing method for CBD that not only extracts cannabidiol from the plant, but also all relevant cannabinoids and terpenes that interact with the CBD and promote its action.


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